Francois wrote:
Although it’s necessary to consider this seriously, the alternative is worse. Also, this is observational in nature with several potential biases that could explain the higher than expected reports in VAERS.
I agree whole-heartedly. This is not a recommendation to NOT get vaccinated, just updating regarding incidence and possible association of covid vaccination with myo/peri-carditis. We are obviously not talking about covid infection related cardiac issues, which is an entirely different conversation, as you know.
'Dad's' just want to know...
I am not an epidemiologist, just a regular clinical, invasive, non-interventional cardiologist...
From 'Up To Date':
Pericarditis:
Acute pericarditis is the most common disorder involving the pericardium. Epidemiologic studies are largely lacking, and the exact incidence and prevalence of acute pericarditis are unknown. However, acute pericarditis is recorded in approximately 0.1 to 0.2 percent of hospitalized patients and 5 percent of patients admitted to the emergency department for nonischemic chest pain.
—In an observational study from an urban area in northern Italy, the incidence of acute pericarditis was 27.7 cases per 100,000 persons per year
—In an observational study from Finland that included 670,409 cardiovascular admissions to 29 hospitals across the country over a 9.5-year period, the standardized incidence rate for pericarditis requiring hospitalization was 3.3 cases per 100,000 person-years
Myocarditis:
In the 2019 Global Burden of Disease report, the rate of myocarditis was 6.1 per 100,000 (95% uncertainty interval [UI] 4.2-8.7 per 100,000) in men and 4.4 per 100,000 (95% UI 3.0-6.3 per 100,000) in women between 35 and 39 years.
The incidence of myocarditis according to International Classification of Diseases diagnosis codes was 22/100,000 or approximately 1.5 million cases in the 2013 world population.