I have actually thought about the is a decent amount. With companies like SRAM and 3t going towards smaller tooth cassettes (and 12sp groups) for the superior gear ratios, this is hurting drive train efficiency. I’ve thought about what if you took it the other way as well, specifically with shimanos 14-28 cassette. If you do the math, using a 64t big ring would be nearly identical to a compact crankset with a standard 11-23. For tri’s, many would find occasions where they would spin out. Therefore, you’d need a 68 or 70t big ring. At that point, I feel aero losses would be worse than any gain in improved chain line efficiency, if you could even fit a gear like that.