I went the truck and camper route but not a 5th wheel. There are obviously pros and cons to all the choices and for us it came down to flexibility. If if I want to stay in a spot for a few days, I dont want to have to pack up my who;e motorhome, put the awning in, etc. if I want to get a few groceries or beer or even go to a restaurant in town (which you will do when you are away for long enough) Additionally, we are big mountain bikers and hikers and the truck allows me some flexibility to easily do day trips and go to trailheads etc. that i wouldn't be comfortable taking my camper. Before some one says you can buy a 4X4 Sprinter conversion, I do know this. There are still forest service roads I will take in my pick up but not in a Sprinter van. Since I don't have a 5th wheel, I am bale to use the pickup box as storage for sports my gear, bikes etc.

Basically a lot depends on your lifestyle and the activities you want to enjoy.

If you are not the KOA type, I strongly recommend a solar panel (preferably installed) and even a small generator to charge up.