Anecdotally I think that eccentric calf raises can help with prevention or rehab of calf issues. There is a specific protocol if you have achilles tendon issues, but I also think that they can be beneficial for calf issues. This is based on my experience and that of friends/athletes/etc. that I have known. It's been said already that the hormonal changes of lifting may not provide as much benefit as originally thought.

These are body weight only and typically standing. I guess you could do seated, but I think that standing is more specific.

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