I use a green cleaner for wiping down the treadmill, and flooring (we have rubber/foam matting). I will use the same cleaner on a rag for wiping weights/kettlebells... I don't have racks set up in our gym. I do lift the matts periodically to sweep the floor underneath. I also try to air it out frequently (open windows and crank the fan to help eliminate some of the humidity (and to get rid of the post workout funk).