I just got my 23andme genetic results back this week - I ran the raw data through geneticgenie to get the 'mutation' report - I've been sick for over 8 months, zero training in that time - what I've learned this week - my B12, methylation and methionine cylces are deficient coz of the mutations:
- mtr a66g homozygous - means got mutation from both parents, so double whammy - impedes use of B12 - my B12 (and folate) blood levels have been abnormal high for over a decade, but its just not getting converted to use in cells - I'm now on daily B12 injections and methylfolate (coz folic acid is synthetic).
I've also got other mutations, heterozygous, so mutation from just one parent including:
- 2 that affect Vitamin D use - so I'm now taking 5000 IU daily
- one that increases homocysteine
- another that increases taurine, ammonia and decreases BH4
and a few more that affect dopamine, glycine.
This knowledge gives me hope that I'll feel better through addressing these issues with supplements - and maybe even get back to training and racing.
Well worth my money.
Advocating for research & treatment for Myalgic Encephalomyelitis (ME).
http://www.meaction.net/about/what-is-me/ "Suck it up, Buttercup"
(me, to myself, every day)