Shimano R7000 mechanical drivetrain. When I am in a cog at the back that is halfway up the block or more (i.e., inboard), the drivetrain makes a decent amount of noise, and the more inboard I go, the louder it is. It's just steady noise...no grinding, clicking, or anything sinister. It just seems that as the RD cage gets stretched/extended with the lower gears, it's just...noisy. Loudest is big ring and 3rd from lowest (the 23t on an 11-28) gear. I don't cross chain any more than that but that's presumably when the RD is under the highest "stretched" condition. In little ring (i.e. when RD is able to "relax" and not be so stretched out) noise goes way down.

Is there any way to mitigate this? Is it unreasonable to expect a silent or near silent mechanical drivetrain when the cage is stretched out? Would any of the following help: upgraded pulley wheels, nicer RD (dura ace 9100), any setup particulars, lubrication of any particular pivots of the RD? I do have some off brand parts: chain is KMC X11, and chainrings are praxis. The noise is not ubiquitous across all gears so don't think these parts are culprits but just to get all info out there about my setup.

My LBS has looked at this. Which is to say I don't have any normal noisemaker culprits with the setup like an out of whack b screw or improper indexing. Everything is as it should be in the eyes of a bike shop...but it's just noisy in those gear combos. Anything I can do?