grassy wrote:
Spending $99 for genotyping at a single locus is absurd. If you want to know your CYP1A2 (or any other gene of interest) genotype, you can pay $99 for genome-wide coverage through 23andme. Ignore the report, download your raw data, and upload to Promethease for another $5. You now have access to look at your genotype at any of 640,000 SNPs (see my example below for rs762551).
Edit: It appears 23andme has a newer feature where you can search through raw data based on gene name or SNP ID, so you don't have to go through Promethease. But I'd still highly recommend Promethease if you're interested at all in looking more through your raw data because it integrates with SNPedia to give way more information about frequency in the population, published literature, etc.
Thanks for the pointer to Premethease. I was having trouble understanding the 23&Me Caffeine report, because it talks about C & T variants rather than C & A, and their descriptions of the C variant sounded more like the A variant in the links described further up in this thread. The 23&Me report lists me as type C:C (as opposed to C:T or T:T), but when I imported the data into Premethease it lists me as A:A.