Cortisone Injections

This was a portion of a recent blog post that I was asked to share with the ST audience. I believe others would benefit from your personal experiences.

What about those of us with shoulder bursitis, a touch of arthritis in the knee, plantar faciitis, those of us whose training - and therefore performance - are limited by injury or age?

With age/pain/injury/wear and tear occasionally comes the visit to the doctors office, and when deemed appropriate the physician may recommend a cortisone injection. Should you find yourself in this situation, this piece may help you work with your medical team to determine if this is the best treatment for you.

So, first, what is cortisone? It’s a corticosteroid, a natural hormone made by the adrenal glands. OK, so what’s an adrenal gland? Humans have two adrenal glands, or supra-renal glands as they’re sometimes called, secondary to their being located on top of the kidneys. This would be near your 12th rib in your back. Like the thyroid, pituitary and pancreas, the adrenals are part of the endocrine system.

Credit for initial synthesis of synthetic cortisone goes to an African-American researcher named Percy Julian. He accomplished this almost 80 years ago.

Cortisone, like aspirin and Advil (ibuprofen), functions as an anti-inflammatory agent. When these drugs are taken orally, the effect is systemic, seen in the whole body. Even when injected into a joint cavity there can be a systemic distribution of the substance. The advantage of injectable cortisone is obvious in that when a particular inflammatory condition is diagnosed, a high concentration of the anti-inflammatory medication can be placed at the identical location.

I’m always asked if these injections hurt. Well, it is a needle but if your skin is “numbed up” first, you hardly feel it. I’ve been told countless times, “That wasn’t so bad” by folks who were prepared for the worst. And, the educated triathlete also asks about the potential for side effects and yes there are a few. Although quite rare, infection following a cortisone shot could be quite serious. However, your physician will thoroughly cleanse your skin with alcohol and betadine to reduce this possibility. Folks with an iodine allergy are cleansed differently. If my office is an example, I’d estimate that I give almost 2,000 of these injections each year, and have for a number of years, but have never had one get infected. Not only that, I know of none occurring in patients of my peers at our hospital. Diabetics should be told that they may see a short term rise in their blood glucose and it’s been reported that very occasionally patients with darker complexions can see a whitening of the skin at the injection site.

The most common negative would be what’s called a cortisone flare, a short term painful reaction which spontaneously resolves in a day or two.

** So, who is a candidate for a cortisone shot?** In my practice, the most common indication is arthritis, particularly of the knee (see previous blog), followed by bursitis of the shoulder. It’s also used very commonly in Tennis Elbow (see previous blog), Morton’s neuroma of the foot, carpal tunnel and trigger fingers just to name a few. They can be repeated if required although, again, the intelligent athlete thinks before acting. In my office, except for knee joint arthritis in the elderly where the plan includes eventual replacement, the limit is usually three. More than this and you actually run the risk of doing more harm than good by sometimes weakening the soft tissue of softening the joint lining cartilage.

So, the take away is that cortisone injections are not an instrument of the devil and when used judiciously with the right indications and diagnostic acumen, they can be quite beneficial to the triathlete.

John

What is the recommended limit for the number of injections in one area?

What is the recommended limit for the number of injections in one area?

 He mentions three, which is what I've always heard, but I remember the reasoning as something like "it's cumulative in the body".  I had an injection for runners knee some 28 or 29 years ago.  Not sure it did much for me, as laying off running was still the path to recovery.

Thanks for the info- nice summary. I have had a couple, used more for diagnosis I suppose, the worst being when my sports med. doc tried to hit my piraformis (sp?) with one. I could barely walk for days.

-Physiojoe

How did that work for you in the long term? The reason I ask is I’ve had piriformis issues in the past as well, but am hesitant to do a cortisone injection. Thanks in advance!

What evidence exists to support the limit on number of injections and the time period over which they are administered? Does this recommendation vary based on the site of injection (ie joint, tendon, muscle)?

Great information Dr.

Thanks

Having my third on my hip tomorrow. Hope it works. Going to ask about the lubrication injection, hopefully that will help to.

kell0, seal98 and 7summits - good questions for which there is no exact right answer. If I had two patients, Joe Triathlete and Joe’s grand dad, both with knee pain, but Joe had bursitis (pes anserine) and grand pa had arthritis, I would stop at 3 for Joe - if we got that far - but if I could keep the elder gent out of the operating room for a knee replacement, I would happily inject him, say semi-annually, for years. So, the site (soft tissue or joint), the the patient and the diagnosis all matter before answering that question. I’m sure there are ST’ers who’ve had back difficulties and under gone “shots in the back” so called epidural steroids. These are frequently done as a series of 3, and it’s not uncommon for a patient to have one series in 2001, another in 2004, etc.

John

Perfect answer Dr. Post!

Last spring they couldn’t figure out what was wrong with my knee, I could barely walk let alone run or bike. They gave me cortisone in my knee and I was honestly able to get on the bike 10 hours later it was amazing. I’ve had a little pain but not much since. I was in shock at how well it worked.

Whats your thoughts on steroid injections for achilles issues? Tendonitis, tedonosis and retrocalcaneal bursitis? Ive had one by an old gp back when I was in med school and it worked great. As I learned more, I found out it puts you at risk for rupture.

Thoughts?

Thanks

How did that work for you in the long term? The reason I ask is I’ve had piriformis issues in the past as well, but am hesitant to do a cortisone injection. Thanks in advance!

Did nothing for me- it was being used as somewhat of a diagnostic. The soreness was the equivalent of deadlifting to failure for 5+ sets, then not having any protein after. Only in the one cheek. It was bad.

I had / have back issues and the top / lateral portion of my left quad tingles and burns off and on. It does this thoughout the day every day, if anything I am actually more comfortable going full gas on the bike than I am sitting still in a chair.

What have you tried so far and what are you trying to make better?

-Physiojoe

If the cortisone shots are done over a much longer period of time, say 5 or 6 years, is the 3 shot rule how most orthopedic doctors look at it. For example, carpal tunnel diagnosed in 2004 with a shot, then another one in 2007, a third in 2010… would they generally go for surgery? (not old patient)

Interesting post, thank you. As an Orthopedic PA for all of 5 weeks (Graduated in December, starting practicing last month), I have a few comments/questions.

Cortisone, like aspirin and Advil (ibuprofen), functions as an anti-inflammatory agent. When these drugs are taken orally, the effect is systemic, seen in the whole body. Even when injected into a joint cavity there can be a systemic distribution of the substance. The advantage of injectable cortisone is obvious in that when a particular inflammatory condition is diagnosed, a high concentration of the anti-inflammatory medication can be placed at the identical location.

Sources? The orthopedic surgeon I work for tells me that while it is believed cortisone’s anti-inflammatory properties make it therapeutic when injected into the knee as treatment for osteoarthrosis, the true mechanism of action is unknown. Any articles, papers, etc would be greatly appreciated. Trying to soak up as much as possible!

I’d love to hear your thoughts of hyaluronic acid and its (more expensive) high molecular weight derivatives as treatment for OA. Do you currently use them? I started my first series of fluoroscopy-guided injections with hyalgan last week, and I’m curious to see how this patient does (medial compartment OA of the knees, left>right). I’m currently using either a medial or lateral approach (as opposed to superior-lateral that I see many folks do). It is the way I was taught, and it’s how my supervising doc does it. Thoughts? Are you also an orthopedic surgeon? I’m assuming yes- 2K injections/yr is quite a bit! Edit: Just read your profile- so I’ve answered that last question myself. Oorah.

tridogs - With regards to old dogs and new tricks, I was taught in residency that the downside of an achilles steroid injection was greater than the upside. So, I’ve not ever done one. But, on occasion, I have injected one with a a xylocaine preparation that was helpful. You might ask rroof as his advice and experience are usually *mainstream *and well thought out.

John

steveandbarbara - good to hear from you again. Yes, I believe you are correct and that most physicians would factor in a time element in making that decision. But, and this is important, I know of a patient who had his tennis elbow injected 13 - 15 times…and the muscle attachment just melted. He needed it reconstructed and the repair will never match up to the original equipment.

John

Having my third on my hip tomorrow. Hope it works. Going to ask about the lubrication injection, hopefully that will help to.

Let me know how that works for you. I know it is helpful in the knee, but might not work in the hip (I had end stage OA and had it replaced) Did have
steroid injections and they worked, as long as there is cartlige present to work on.

I have decided to try the euflexxa injections into my hip. They have only been used in the knee but since i have little cartiledge left, the Dr. thinks it may help build a membrane that will help reduce friction. This will be a three week series starting next Friday. I’ll let you all know how it goes…fingers crossed.

Were you able to get insurance to pay for unindicated use (hip) since it is for the knee? My brother has OA of the hip (hard core swimmer/national level in his day) and requires a hip replacement or resurfacing but can’t get it done until major problems in his teeth/gums are taken care of.