If your hip angle is very closed at top dead center you may be stretching the fabric in that area of your garment tight. In doing so it can rub across the skin. No amount of chamois cream will delay that rub indefinaty.
Check if this is the case.
As a matter of course you ought to seek a bike fit so you are bio mechanically efficient on the bike.
Once you are confident your position is correct then find clothing which works with your anatomy in this position.
IME chamois pad thickness and more lube have proven to be red herrings here it’s been due to fabric placement and fit creating pull on the fabric and hence rub…
I dealt with this quite a bit after a refit. What worked for me:
Let the skin heal first. It’s hard to maintain training and healing at the same time. Be diligent to keep it clean and let it heal up. There are horror stories if you get an infection.
I noticed tighter fitting tri shorts (ie very little pad) worked best
Lube up, it will delay the chaffe at least for the shorter rides.
If you feel the chaffing during a longer ride, move around and do whatever it takes to not let it get worse. I stopped once and bought Vaseline.
For me, once the skin was chaffed then healed, it never happened again. I think new areas of my skin needed to be toughened a bit.
“Retul” is a tool only and sadly no guarantee of a good fit.
The person using it though may be…
Let’s assume you got a good result, and your fit is suitable.
While riding can you see/ feel fabric pulled tight when you pedal.
Does this change when in extensions vs pursuit?
If no to all the above then you have something else going on.
If you are riding JOF or Adamo style then this part of your leg shouldn’t even be touching the saddle side, unless you are sitting very far back on it or have it too high and your hips are rocking at bottom dead Ctr .
Consider these two aspects and see if either may be contributing.
I had a retul bike fit so i’m sure it’s not the fit…the problem seems worse with bike shorts vs tri shorts. should I try a saddle with no cutout?
I had the same issue as you. I found that heavily padded shorts were worse because the chamois fabric was bunching at the sides of the nose on my saddle (Adamo ISM). In tri shorts it has not been an issue.
When wearing a thicker chamois I now consciously arrange the fabric and myself so as to minimize this. Occasionally during a session I have to move around a bit on the seat to get the fabric re-adjusted too.
One side or both sides?
I would talk to your fitter first, as they should have lots of data to analyze.
Could be a thing you just have to get used to, could be a result from something in your mechanics, could be wardrobe, or could be a combination of the above:)
Both sides, they have a good saddle demo program so they suggested trying new ones first, maybe my position has changed since I first got fit? They do offer free adjustment fittings so that’s a good idea