Calf pain associated with too much cushion?

I purchased a new set of shoes yesterday. They are Nike Pegasus. Did a 6 mile run and my calfs were really, really sore. I also have just started using a foam roller. So possible it is not the shoes.

I went though a complete shoe sizing. First time. At a well known running shoe store.

I was thinking trying the Vomero which even has more padding. Also was going to try the Asics Cumulus.

I also have really tight muscles all throughout my legs so the issue also might be these tight muscles are causing bad mechanics.