If I overtightened my cycling shoes could that be the cause of sharp pain on my instep when running…so much that’s it’s making me stop for the moment? It doesn’t hurt when unweighted or even so much when walking, but running really hurts!
Yup - literally just saw a guy with this same issue.
Of course, could be a lot of other things as well … 
While I realize it could be a bazillion other things, that seems to be the only reason for me since I had a race on Wed…and my foot went numb…then road again thurs…with similar problems then friday morning…ouch! Sat, run…almost couldn’t keep on it. It seems to be getting a little better, am just hoping it isn’t going to sideline my training too much.