I originally asked the question in another thread but now I am really curious. Anybody knowledgeable about this? Maybe somebody who (although he is not a scientist) is nonetheless a physician? 
To the point:
1/ Do you produce less testosterone if you only have one testicle (one ovary) or does the body compensate and just produces more from the remaining organ?
2/ Do you get a TUE (Therapeutic Use Exemption) if you are in this predicament?
Edit: DUE => TUE
I originally asked the question in another thread but now I am really curious. Anybody knowledgeable about this? Maybe somebody who (although he is not a scientist) is nonetheless a physician?
To the point:
1/ Do you produce less testosterone if you only have one testicle (one ovary) or does the body compensate and just produces more from the remaining organ?
2/ Do you get a DUE (Drug Use Exemption) if you are in this predicament?
Low testosterone levels are pretty rare but they do occur. I think I had only one in my practice (at least that I knew about) and he was on something or had a condition that suppressed testosterone production, as I remember. If he were having symptoms associated with a low level then I suspect he would be given a DUE to allow him to return to normal but not supra-normal. I would be surprised if this is the case, however, as I canât imagine the whole cycling world not knowing about it.
the body compensates. losing a testicle doesnât reduce your t levels.
we have two so that we have a spare basically.
pretty cool design =)
I originally asked the que
stion in another thread but now I am really curious. Anybody knowledgeable about this? Maybe somebody who (although he is not a scientist) is nonetheless a physician?
To the point:
1/ Do you produce less testosterone if you only have one testicle (one ovary) or does the body compensate and just produces more from the remaining organ?
2/ Do you get a DUE (Drug Use Exemption) if you are in this predicament?
Thank you to the both of you for the prompt and detailed answer. Back to our regular programmingâŚ
Low levels of testosterone are not rare (at all) among the population of endurance athletes. Itâs well documented that the levels of serum testosterone is decreased to sub-normal levels by intense and/or prolonged workout phases.
Low levels of testosterone are not rare (at all) among the population of endurance athletes. Itâs well documented that the levels of serum testosterone is decreased to sub-normal levels by intense and/or prolonged workout phases.
Thanks for the info. Then, I suspect, he would not be given an exemption, even if he were symptomatically low. It would be a HTFU situation with out the H perhaps.
Olaf Sabatschus wasnât given one. Donât think the UCI would give Lance one.
Olaf Sabatschus wasnât given one. Donât think the UCI would give Lance one.
As I googled what you said to confirm I saw a couple of articles that mentioned that testoserone usually doesnât drop after orchiectomy. But, it seems to in endurance athletes. So, I can now understand why.
And there is a bunch of the 50 plus guys using it as a PED and not in the bedroom.
First off itâs not the UCI that issues the TUE (therapeutic Use Exemption, unless they changed the name, because i used to be on one for my asthma medication in university), itâs the national anti-doping agency (under the WADA code). Secondly, I doubt for something like that, they would give one because of the room for abuse. You issue one, and then everybodyâs doctor finds some excuse to prescribe testosterone and to get a TUE issued. Just like when you look at it, virtually every pro cyclist has âasthmaâ so that they can use the puffers to open up their airways moreâŚ
Chris Boardman retired partly because he needed Testosterone treatment and couldnât have gotten a TUE.
Just like when you look at it, virtually every pro cyclist has âasthmaâ so that they can use the puffers to open up their airways moreâŚ
I remember Rappstar explaining that allergy medication was only beneficial if you actually have allergies i.e. itâs not a PED and the federations couldnât care less about granting exemptions. Now, itâs not to say that there is not a placebo effect.
Although I pretty much take Rappstarâs scientific/factual comments at face value, I tried to find an article on the American College of Sports Medicine and PubMed websites to no avail. Anybody with a definite answer?
PS: TUE indeed⌠got my DUI and TUE mixed up maybe.
Is it the low level of testosterone, or the high level of cortisol relative to testosterone? Or is that a different animal altogether?
/personal experience
some details of asthma meds and how they work, with citations, are here.
Basically Rappstar is right.
many of them, as a side effect, will also affect heart rate.
that obviously doesnât translate to performance necessarily, but, subjectively, some of the emergency inhalers will make you feel like you just chugged a red bull for a few seconds.
some details of asthma meds and how they work, with citations, are here.
Basically Rappstar is right.
I have suffered from this on many an occassion from training too hard.
Except, unfortunately, there are some new classes of asthma medication which a number of researchers have decided belong on the banned list, but are not (or were not, last I checked). They are based on a derivative of the caffeine molecule, at least thatâs based on my relatively poor biochem knowledge. There was a bunch of stuff right before Beijing, as you might imagine, since everyone had exemptions for the poor air. So itâs a mixed bag - at best - now on inhalers. Some are really only placebo for those who donât need them. But some are not.
hm interesting. Every emergency inhaler Iâve encountered has been albuterol-based. Maybe I should ask my doctor about some new drugs
Testosterone: When we exercise regularly testosterone levels rise. It helps recovery and performance improves. But this doesnât go on forever. At some point testosterone levels stop rising and then fall. Recovery time increases and the body can break down. Everyone is different. Some of us can handle more training and some less. What drug cheats do with steroids is to artificially support testosterone levels (or raise them) allowing for ever greater training and thus further performance enhancement when others would develop overtraining. Of course itâs more complicated (textbook).