You can read about the relative advantages of the different wheels on our tech pages of the site:
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http://www.zipp.com/Default.aspx?tabid=103>
On the wind tunnel graphs 0.1lbs of drag is the equivalent of 6 watts, so it really depends on what wheels you are comparing. Also we have a link to Tour Magazine's wind tunnel test which extrapolates time savings of various aero wheels. They predict the time savings of 808's over Ksyriums for 40k as being 68 seconds, wheels using the previous generation 404 rims came in at 62 and 50 seconds faster. These assume a rider outputting 300 watts, the time savings will increase slightly with lower wattage.
http://www.zipp.com/...bid/155/Default.aspx The fastest wheel for a 70.3 will be the fastest wheel you are comfortable riding, the 808 is considered the fastest non-disc wheel on the market right now, but is a little deep for some people (although it does have 30% less side force than a 3 spoke and about 15% less side force than 100mm rim in a cross-wind) hence the 606 which is a 404 front with 808 rear really seems to be the setup for IM/HIM distance (winning 5 categoreis at Kona), for larger riders the full 808 is generally no problem (I weigh 155 and ride 808's on my road bike daily) and for smaller riders the 404 or 343 (303 front/404 rear) are very good options, but it is my experience is that the 343 is only really beneficial for riders under 120 lbs or who are VERY concerned about bike handling.
Adding a disc rear will also speed things up a bit, but the margins are small, the disc is about 4-6 seconds per 40k faster than the 808, so for some people that is more than worth it.
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