Yes - I've done it to address stretched out ligaments in my SI joint. Had excellent results, however I have had to get periodic prolotherapy injections as follow-up. About every 2 years or so I'll start feeling loose in my SI joint, with pain that builds - when that happens I get another round of prolotherapy.

How was the pain after? At what point were you able to go back to work, drive, etc?

So..I was never unable to work (white collar desk person) but driving was limited. My ability to train was what was most limited - besides discomfort in my back I had recurring injuries elsewhere. It was a gradual ramp back up, combined with PT. I'd say that 6 weeks after the shots I was considerably improved. Note that we were also treating a torn hamstring with PRP at the same time.

One thing to remember - I've done PRP for both the SI Joint/hamstring and for my right ankle (much more recently). In both cases, the first 10 days I was WORSE after the injections - then things turned around.

I should also note that each time I've had PRP, I've taken 2 days in bed and then just resumed PT and activity as I was before the injections. So the improvement I've seen from each cannot be attributed to rest.

Thank you for your experience