I use an Azoto on my road bike. I like it. I like it a lot. I find it more comfortable than the same saddle on my tri bike.

I tried it once and I did not like it. I love it on my tri bike though. Go figure.

Ditto what Art said. The big cushy nose ends up pressed into parts of me that I don't want pressed. On the road bike, I like all the weight on my sitz bones. On the tri bike, that's just not possible, and the Azoto makes the best of a bad situation.