So please obviously know this is a bit of a guessing game without seeing you, but my top two things would be:
1) peroneal (otherwise known as fibular) nerve entrapment
2) or it is actually coming from your back.
The shoes *shouldn't* be too much of an issue except that often people tend to over correct what they see. I am not a barefoot running person (except that it has been great for business), but the one thing the barefoot craze has done is bring attention to the fact that we don't have to correct everything we see. So you pronate when you walk, some pronation is normal. Do you pronate when you run, run at speed, are running fatigued? We have to take this and the musculature of your foot into account. From what I understand the 2160 is not a massive correction shoe - so may not be the main culprit.
My recommendations would be:
Stretch your calves: good old runners stretch (gastric stretch) - then same position bend your back knee (soleus stretch)
Stretch your hamstrings
Stretch your piriformis (pidgin pose-ish in yoga)
roll out with foam roller or stick the outside of your leg - ITB and fibular muscles.
I can send you picture if you want - just send along your email!
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Thrive Kinematics Physical Therapy - http://www.facebook.com/...8178667572974?ref=hl