There seems to be a permanent sore there now[/quote]
Last year my wife was experiencing the same type of chafing while riding her road bike and the problem was somewhat exacerbated by her tt/tri bike (expecially severe when it was hot/humid) and the resolution was resolved with several items to include better riding shorts, but was mainly related to issues with proper bike fit/cleat alignment. Of course the solution was complicated by the fact that my wife has the most highly calibrated knees of anyone I know as she can tell when her saddle is even 1mm to high . She also cants her knees into the frame at the top of the pedal stroke - the right knee more so than the left such that it can and did very quickly wear through the material on the right side of her saddle - and she would get exactly the same type of chafing/saddle sores as you descirbed (looks like a lump/cyst).

At 5'8" you would think she could ride 172.5mm cranks but with relatively short legs compared to her torso, I opted to swap out her cranks for 170s. Next, when she was riding in a straigh line, her upper body tended to be positioned more like she was cornering and after adding/positoning a couple wedges to one of her shoes to account for a slight leg length discrepancy, this is no longer the case. Finally, we tried several chamois creams and while we both like Assos, it does not last long when riding and is more for after care but she did find that Dermatech's 'Crotch Guard' (http://www.dermatect.com/...hguard.php?item_id=5) lasted quite a bit longer than other products and except for the hotest days, has all but eliminated her issue with chafing/saddle sores. At this point other than the physical challenges of riding (aka wind and hills), she is a very happy camper but I observe that despite no more problems with chafing, the evidence of the problem still remains in the area in question which I can only surmise this is residual scar tissue. I can't help wonder what can be done to reduce and/or eliminate that but for some reason suggestions concerning applying acetone or seeing a dermatolgist for an application of nitrogen don't go over too well!

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¯\_(ツ)_/¯

I have the same exact issue in the same place. I haven't gotten it to completely go away yet but a few things have helped some for me--I'm interested to see what happens as I'm training for my first IM this year and things will get longer on the bike than before.

First, it gets better as I ride more often. Next, I only wear tri shorts now--and wear ones that don't have seams on the inner leg and have gusseted seams inside. Shebeest is so far my favorite. I bodyglide me and I also rub bodyglide along the seams in the crotch area on my shorts before I put them on. Then, I add a layer of Assos to my skin before I head out. I tried a bunch of saddles last summer--I'm not 100% sold on it yet but the best one so far, that I'm still using, is the Blackwell Flow.