I suggest you number your goals in order of priority. Make sure they're specific (for example, don't say you want to lose weight, say you want to lose 10 lbs by July 31st).
To start things off, here are my goals for 2008 (revised 7/21/08):
1. Run a minimum of 5 times a week, every week.
2. Break 4 hrs in a fall marathon. I really want to BQ (need a 3:50), but I don't think I can get there this year. I want to get as close as possible and I definitely thinking breaking 4 hrs is do-able.
No marathon for me this year. Instead I want to break 1:53 in a half marathon. This will be a good challenge for me. Still going long (love to run long), but short enough that I can concentrate on getting faster and not just going longer.
3. Lose 20 lbs by September 30, 2008.
4. Survive American Zofingen.
Now that I won't be slogging out the run miles, I want to do more than just survive AmZof. My training plan will now consist of more biking than I originally planned. Getting through the bike in reasonable condition will be the key to this race, so I've got to get some good legs on the bike before October.