You're good. You're quite a bit away from the problematic portions of Mulholland (Rock Store, bridge by Troutdale), so no problem there. If it's gusty and you are on deep wheels, the top portion of the Topanga descent can be puckering. Will you be riding a road bike or TT/tri bike? I would recommend the former, given the climbing and descending, unless you're looking for specific work on the TT/tri bike.

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Amateur recreational hobbyist cyclist
https://www.strava.com/athletes/337152
https://vimeo.com/user11846099

it'll either be road or gravel. i don't consider the rock store part of mulholland an issue, so i guess we're good. i spend more time in the western parts. decker, latigo, encinal, yerba buena, potrero. i don't know the eastern parts as well. i went up los flores before and then down stunt to mulholland, but i've never done piuma, tuna, old topanga.

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Dan Empfield
aka Slowman

You're not descending the fast section of Tuna, which takes you to PCH, and that top section is NBD. Fernwood is a bit steep and twisty and there are driveways on both sides all the way down, but the residents there know their road and usually the worst result we encounter there is getting stuck behind a slow-moving car. We run our club TT on Piuma + Schueren and you'll be doing almost all of that segment (you'll cut off the first bit by starting at Cold Canyon rather than Las Virgenes) and the only thing to note there is the left-hander to Schueren is a bit off-camber and you're hitting it after a fast downhill so most years a rider or two will overcook that corner and end up in the dirt shoulder. But assuming you're not racing your route and trying to squeeze out every last second, you won't have any issues there.

You've selected a great, challenging route with some great views off Piuma and at the top of Saddle Peak. You're likely to encounter various cyclists at the top of Saddle Peak - it's a bit of a nexus/junction with Stunt, Schueren, and Saddle Peak intersecting there.

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Amateur recreational hobbyist cyclist
https://www.strava.com/athletes/337152
https://vimeo.com/user11846099