It's probably an eventuality.

I wonder if it would also need to be stored at -94 F? That would limit it's practicality for most, would it not?

Edit - But on second thought, you may need to do it only once and have the effects for the rest of your life. That creates some crazy new wrinkles in doping enforcement.

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Ed O'Malley
www.VeloVetta.com
Founder of VeloVetta Cycling Shoes
Instagram • Facebook

This technology does not modify your genetic code. Each bit of mRNA is basically just an order form that tells a cell to make a protein.

And mRNA is extremely fragile, it does not last long in the body. This fragility is the reason that mRNA treatments weren't available decades ago, and why the mRNA vaccines need to be stored very cold.

But presumably they make the protein for a long time? Or is it only long enough for your immune system to recognize it? Obviously I am not a biochemist....

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Ed O'Malley
www.VeloVetta.com
Founder of VeloVetta Cycling Shoes
Instagram • Facebook

it has been a while since biochemisry, and maybe I misinterpreted your reply, but mRNA is no t likely a long term result and if I interpret your answer one way I think we are saying the same thing,

but as I recall the mRNA carries the protein message to the ribosomes which every cell has. So if there is some mRNA around it will eventually find a ribosome and then the transcription into a protein happens. Once the mRNA is used to get the message to the ribosome I do not think it can be read again otherwise you would not have any protein ever stop being made which would be an obvious problem, So in the case of a vaccine all that needs to happen is that you produce some of the protein, the immune system amplifies as needed to develop immunity. in the case of doping I think one injection would only produce a limited amount of EPO for instance and that to get more would require further injections. I would be interested in knowing more about this though.

Also my understanding (and maybe what you are saying as well) is why something like crispr gene editing is so interesting once a gene is edited as long as the cell keeps dividing and the cell line lives it will produce the protein. That would mean in the case of EPO it would continue to be produced. Not sure if in the long run that would be good or bad for health.

the current covid 'vaccines' are being developed to use mRNA (pfizer version).

but playing with gods code, as other doping drugs has its trade offs:

https://www.mskcc.org/news/scientists-find-cancer-drivers-hiding-rna-not-dna