In a recent magazine of one of the Siemens branches, I noticed an article about the Trek Madone. Apparently, they used software that automatically generates different designs and tries to optimize those as much as possible. It's a marketing story, but a nice example on what's going on behind the scenes.

https://www.plm.automation.siemens.com/...sue2_tcm55-61517.pdf
Pages 28 - 37