Bunny, I love that you keep recommending my wheelset!
I've got as Fly for my front wheel and weigh 200 pounds. Dave at Nimble recommended 24 spokes, which I got, and which I thought was a bit conservative. I also got mine built up around a Chris King hub and it's oh-so nice. The wheel is beautiful, wicked light, and great to ride. It's not a super deep rim, but it is an aero rim. Nimble makes some big claims about its performance vs something like a 404, but I'm not going to speculate on it. Hopefully in a few weeks I'll have some very informal and unscientific test data of my own but it will be vs. my heavier but fast rolling Rolfs.
Nimble also offers a HorseFly which is a Clydesdale version of the Fly. It consists of a more substantial rim (the rims are crazy strong) and a higher spoke count range. If you're interested, give them a call. Dave is great to talk to and their customer service is great. I'm now a big Nimble fan.
http://www.nimble.net One thing about the rim depth. I intentionally went with a shallow rim vs something like the 404 as this is currently my only front race wheel and wanted something I could use on any course in any condition. My next front wheel will probably be something like a trispoke or a 404. Too bad they won't be as light as my Fly.