It depends on

• the type of terrain you live in,
• how strong of a rider you are
• whether you like to spin fast or not.
• the size of your crank.
• If you like prefer small gear jumps or don't mind large ones.

In other words, too many variables.

But if you're just taking a poll, I ride on mostly rolling terrain and am not particularly strong. I run 50-36 up front and 12-28 in back. I find 36x28 is enough for most climbs and 50x12 is big enough for most downhills. I occasionally spin out on long steep downs but it's worth it to have the 16-tooth cog that I'd be missing with 11-28