This isn't actually true. You can use a plug, like a "Bacon Strip" or "Dynaplug." Putting a tube in a TL tire is not the first-line fix to a hole. The plugs are actually even faster than changing a tube on a standard clincher. You don't even have to take the wheel off. You just jam the plug in, re-inflate tire and go. Yes, you might have a little bit of sticky latex mess on your calves, but it makes it easier to find the hole, and I'd rather some latex on my cleanly shaven calves (this is key!) than grease all over my hands (which I use to eat).

Any hole that a Dynaplug can't patch is probably so large you'd be equally screwed running tubes unless you happen to race with a $1 bill or MTB patch kit.

I'd say try it out and decide for yourself. I've been running Zipp Tangente Speed TL tires on Zipp ZSWs for the last month or so without a single flat, and I've been kind of deliberately trying to kill them.... deliberately riding through the occasional roadside pile of glass, etc. Not a single flat yet. It's also been SUPER nice training at 75 PSI. The ride is like butter.

Now, I haven't yet seen crr or aero data on the Zipp tires, but am thinking I'll train on them and then switch over to a fresh set of 5000 TL a week or so before my first summer "A" race just to do a few test tides to make sure everything is seated properly.

But I'm still new at this TL thing, so my opinion could change!