Hello damon.lebeouf and All, http://www.businessinsider.com/...ld-slow-aging-2018-1
Most research indicates that the people who live longest and stay healthy tend to eat a largely plant-based pescatarian diet that's relatively low in protein. Longo thinks this is ideal â€” a mostly vegan and fish-based lifestyle, though one in which moderate consumption of wine and coffee are permitted.
For someone in good health who is eating like this and getting regular exercise, he thinks the FMD might be beneficial to do twice a year.
For healthy people eating a more "normal" diet, he wrote that the FMD might be beneficial once every four or five months. People with at least two risk factors for cancer, diabetes, or heart disease who are overweight could consider doing the FMD once a month, Longo says."
THE FASTING-MIMICKING DIET
People on the FMD eat normally for 25 days, but the five-day fast portion is no joke
On those days, participants eat a specific blend of nutrients that amount to 1,100 calories on the first day and 800 calories per day on days two through five.
Nutritionally, most of these calories come from complex carbohydrates (like vegetables), healthy fats (olive oil), and plant-based protein (from nuts).
Although it's still far too early to say whether doing the FMD every so often will actually prolong life in the long term, the basic idea is appealing. Fasting is known to trigger physical changes
that seem to be associated with longer life and disease prevention. Early clinical trials indicate
that restricting calorie intake seems to trigger similarly promising physical changes in people, which is why it's sometimes discussed as a potential anti-aging intervention.
"The diet itself is remarkably simple.
For five consecutive days each month, participants drastically limit their caloric intake (hence, "fasting mimicking") by up to two-thirds. The first day they'd consume 1,090 calories (10% protein, 56% fat, 34% carbohydrate), and for days two through five they'd consume just 725 calories (9% protein, 44% fat, 47% carbohydrate). Most of those carbohydrates came in the form of vegetables.
That's not easy. Bowes writes that many participants experienced profound headaches and dehydration. Mentally, he says he alternated between exhaustion and an alert sense of clear-mindedness.
But for the remaining 25 days of the month, study participants ate whatever they normally would.
Researchers have long been fascinated by the health benefits associated with temporary fasting
â€” the idea behind this diet is to get those benefits without having to do something quite so drastic." https://academic.oup.com/...ticle/73/1/1/4733393 https://academic.oup.com/...ticle/73/1/4/3834057
"The CALERIE trial randomized N
= 220 nonobese adults to 25% caloric restriction (n
= 145; 11.7% caloric restriction was achieved, on average) or to maintain current diet (n
= 75) for 2 years. We analyzed biomarker data collected at baseline, 12-, and 24-month follow-up assessments. We applied published biomarker algorithms to these data to calculate two biological age measures, Klemeraâ€“Doubal Method Biological Age and homeostatic dysregulation. Intent-to-treat analysis using mixed-effects growth models of within-person change over time tested if caloric restriction slowed increase in measures of biological aging across follow-up. Analyses of both measures indicated caloric restriction slowed biological aging. Weight loss did not account for the observed effects. Results suggest future directions for testing of geroprotective therapies in humans."
+1 mph Faster